BRONCHIAL ASTHMA ((Tamaka Swasa, Dama)

                BRONCHIAL ASTHMA 

Bronchial Asthma, दमा , सांस फूलना, तमक श्वास, 
                  
                                    "Life starts with breath, and ends with breathlessness"


In 2019 asthma affected approximately 262 million people and caused approximately 461,000 deaths. Most of the deaths occurred in the developing world . Asthma often begins in childhood, and the rates have increased significantly since the 1960s. Asthma was recognized as early as Ancient Egypt.  The word "asthma" is from the Greek ἆσθμαâsthma, which means "panting". The word 'asthma' has a long history. Derived from the Sanskrit vayu meaning 'wind', it found its way into Greek  as α' ίω (to blow), and through Latin entered Middle English as asma. The term was not originally associated with disease.
According to Ayurveda : The underlying cause of all asthmatic conditions is-'Increased Kapha dosha in Stomach'. From there it progresses into the lungs, trachea and bronchi. 'Kapha' is one of the three energies or doshas (Vata, pitta and Kapha) responsible for balancing the overall health. These kapha collect in the digestive system and are aggravated by a wintry conditions affecting the lungs.
                                                   “Learn to manage it on your own”
 
Introduction
Asthma is a long term inflammatory disease of the airways  of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. 
Cause
Asthma is caused by a combination of complex and incompletely understood environmental and genetic interactions.These influence both its severity and its responsiveness to treatment. It is believed that the recent increased rates of asthma are due to changing epigenetics (heritable factors other than those related to the DNA sequence) and a changing living environment. Asthma that starts before the age of 12 years old is more likely due to genetic influence, while onset after age 12 is more likely due to environmental influence.
  • Asthma is thought to be caused by a combination of genetic and environmental factors.  Environmental factors include exposure to air-pollution and allergens. 
  • Other potential triggers include medications such as aspirin and beta blockers

Environmental

  • Many environmental factors have been associated with asthmas' development and exacerbation, including allergens, air pollution, and other environmental chemicals. There are some substances that are known to cause asthma in exposed people and they are called asthmagens. Some common asthmagens include ammonia, latex, pesticides, solder and welding fumes, metal or wood dusts, spraying of isocyanate paint in vehicle repair, formaldehyde, glutaraldehyde, anhydrides, glues, dyes, metal working fluids, oil mists, molds. 
  • Smoking during pregnancy and after delivery is associated with a greater risk of asthma-like symptoms.
  • Low air- quality  from environmental factors such as traffic pollution or high ozone levels has been associated with both asthma development and increased asthma severity. Over half of cases in children in the United States occur in areas when air quality is low.
  • Exposure to indoor volatile organic compounds may be a trigger for asthma; formaldehyde exposure, for example, has a positive association. Phthalates in certain types of PVC  are associated with asthma in both children and adults. While exposure to pesticides is linked to the development of asthma, a cause and effect relationship has yet to be established. A meta analysis concluded gas stoves are a major risk factor for asthma, finding around one in eight cases in the U.S. could be attributed to these.
  • The majority of the evidence does not support a causal role between paracetamol (acetaminophen) or antibiotic use and asthma. A 2014 systematic review found that the association between paracetamol use and asthma disappeared when respiratory infections were taken into account. Maternal psychological stress during pregnancy is a risk factor for the child to develop asthma.
  • Asthma is associated with exposure to indoor allergens. Common indoor allergens include dust mites, cockroaches, animal dander (fragments of fur or feathers), and mold. Efforts to decrease dust mites have been found to be ineffective on symptoms in sensitized subjects.Weak evidence suggests that efforts to decrease mold by repairing buildings may help improve asthma symptoms in adults. Certain viral respiratory infections, such as respiratory syncytial  virus and rhinovirus may increase the risk of developing asthma when acquired as young children. Certain other infections, however, may decrease the risk.

  • Hygiene hypothesis
The hygiene hypothesis  attempts to explain the increased rates of asthma worldwide as a direct and unintended result of reduced exposure, during childhood, to non-pathogenic bacteria and viruses. It has been proposed that the reduced exposure to bacteria and viruses is due, in part, to increased cleanliness and decreased family size in modern societies. Exposure to bacterial endotoxin in early childhood may prevent the development of asthma, but exposure at an older age may provoke bronchoconstriction. Evidence supporting the hygiene hypothesis includes lower rates of asthma on farms and in households with pets.

Use of antibiotics in early life has been linked to the development of asthma Also, delivery via caesarean section  is associated with an increased risk (estimated at 20–80%) of asthma – this increased risk is attributed to the lack of healthy bacterial colonization that the newborn would have acquired from passage through the birth canal. There is a link between asthma and the degree of affluence which may be related to the hygiene hypothesis as less affluent individuals often have more exposure to bacteria and viruses.

Genetic

Family history is a risk factor for asthma, with many different genes being implicated. If one identical twin is affected, the probability of the other having the disease is approximately 25%. By the end of 2005, 25 genes had been associated with asthma in six or more separate populations, including GSTM1,IL10,CTLA,SPINK5-4,LTC45,IL4R AND ADAM33, among others. Many of these genes are related to the immune system or modulating inflammation. Even among this list of genes supported by highly replicated studies, results have not been consistent among all populations tested. In 2006 over 100 genes were associated with asthma in one genetic association study alone; more continue to be found.


Some genetic variants may only cause asthma when they are combined with specific environmental exposures. An example is a specific single nucleotide polymorphism in the CD14 region and exposure to endotoxin (a bacterial product). Endotoxin exposure can come from several environmental sources including tobacco smoke, dogs, and farms. Risk for asthma, then, is determined by both a person's genetics and the level of endotoxin exposure.

CD14-endotoxin interaction based on CD14 SNP C-159T
Endotoxin levelsCC genotypeTT genotype
High exposureLow riskHigh risk
Low exposureHigh riskLow risk
Medical conditions



A triad of atopic eczema, allergic rhinitis and asthma is called atopy. The strongest risk factor for developing asthma is a history of atopic disease. with asthma occurring at a much greater rate in those who have either eczema or hay fever. Asthma has been associated with eosinophilic granulomatosis with polyangiitis (formerly known as Churg–Strauss syndrome), an autoimmune disease and vasculitis. Individuals with certain types of urticaria may also experience symptoms of asthma.
Atopic eczema

Atrophic rhinitis

xxxxx

There is a correlation between obesity and the risk of asthma with both having increased in recent years. Several factors may be at play including decreased respiratory function due to a buildup of fat and the fact that adipose tissue leads to a pro-inflammatory state.
Obesity




Beta blocker medications such as propranolol can trigger asthma in those who are susceptible. Cardioselective beta-blockers, however, appear safe in those with mild or moderate disease. Other medications that can cause problems in asthmatics are angiotensin-converting enzyme inhibitors, aspirin and NSAIDs. Use of acid suppressing medication (proton pump inhibitors and H2 blockers) during pregnancy is associated with an increased risk of asthma in the child.


People with breathing disorders such as asthma, bronchitis, or emphysema should not take propranolol. 
                                             ASPIRIN is contraindicated in asthma.
Signs & Symptoms
  • Recurring episodes of  wheezing, coughing, chest tightnessshortness of breath.
  •  These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise.
  • Sputum may be produced from the lung by coughing but is often hard to bring up.
  • During recovery from an asthma attack (exacerbation), it may appear pus like due to high levels of white blood cells called eosinophils.
  •  Symptoms are usually worse at night and in the early morning or in response to exercise or cold air. 
  • Some people with asthma rarely experience symptoms, usually in response to triggers, whereas others may react frequently and readily and experience persistent symptoms.
Associated conditions
A number of other health conditions occur more frequently in people with asthma, including 
  • Gastroesophageal reflux disease (GERD), 
  • Rhinosinusitis, and 
  • Obstructive sleep apnea. 
  • Psychological disorders are also more common, with anxiety disorders occurring in between 16 and 52% and mood disorders in 14–41%. It is not known whether asthma causes psychological problems or psychological problems lead to asthma. 
  • Current asthma, but not former asthma, is associated with increased all-cause mortality, heart disease mortality, and chronic lower respiratory tract disease mortality (LRTD). 
  • Asthma, particularly severe asthma, is strongly associated with development of chronic obstructive pulmonary disease (COPD). 
  • Those with asthma, especially if it is poorly controlled, are at increased risk for radiocontrast reactions.
Cavities occur more often in people with asthma. This may be related to the effect of beta 2 agonists  decreasing saliva. These medications may also increase the risk of dental erosion.
Exacerbation
Some individuals will have stable asthma for weeks or months and then suddenly develop an episode of acute asthma. Different individuals react to various factors in different ways. Most individuals can develop severe exacerbation from a number of triggering agents.

Home factors that can lead to exacerbation of asthma include dust, animal dander (especially cat and dog hair), cockroach allergens  and mold. Perfumes are a common cause of acute attacks in women and children. Both viral and bacterial infections of the upper respiratory tract can worsen the disease. Psychological stress may worsen symptoms – it is thought that stress alters the immune system and thus increases the airway inflammatory response to allergens and irritants.

Asthma exacerbations in school‐aged children peak in autumn, shortly after children return to school. This might reflect a combination of factors, including poor treatment adherence, increased allergen and viral exposure, and altered immune tolerance. There is limited evidence to guide possible approaches to reducing autumn exacerbations, but while costly, seasonal omalizumab treatment from four to six weeks before school return may reduce autumn asthma exacerbations.

Pathophysiology

Figure A shows the location of the lungs and airways in the body. Figure B shows a cross-section of a normal airway. Figure C shows a cross-section of an airway during asthma symptoms. 


Asthma Obstruction of the lumen of the bronchiole by mucoid exudate, goblet cell metaplasia, epithelial basement membrane thickening and severe inflammation of bronchiole.



Diagram of Asthma

Asthma is the result of chronic inflammation  of the conducting zone  of the airways (most especially the bronchi and bronchioles), which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. The narrowing is typically reversible with or without treatment.

Occasionally the airways themselves change. Typical changes in the airways include an increase in eosinophils  and thickening of the lamina reticularis . Chronically the airways' smooth muscle may increase in size along with an increase in the numbers of mucous glands. Other cell types involved include T lymphocytes, macrophages and neutrophils, and neutrophils. There may also be involvement of other components of the immune system, including cytokines, chemokines, histamines, and leukotrienes  among others.

Complications
  • Sinusitis
  • Obstructive sleep apnea
Diagnosis
  • Chest bilateral Rhonchi +++
  • Weight - Overweight
  • BMI -More than 30
  • Pulse
  • BP
History of allergy
Previous ICU admission

Auscultation -widespread wheeze.
X-Ray Chest PA AND Lateral view. To  rule out any other diseases that may be causing similar symptoms. Lower Zone increased markings. Lung field K crepitations.
Blood test: Complete Blood Count (CBC) , and blood IgE levels.
IGg Levels : E (IgE) Serum ELFA     520 KUI/L(raised)    Normal - < 150
The level of serum IgE rises during childhood and reaches adult levels during the teens.. IgE is a mediator of the allergic response. Patients with atrophic disease, including allergic asthma, allergic rhinitis, and atopic dermatitis commonly have moderately elevated serum IgE levels. Total serum IgE levels may also be elevated in the presence of some clinical conditions that are not related to allergy. These clinical conditions include parasitic infections, immunodeficiency states, autoimmune diseases, Hodgkin's disease, bronchopulmonary aspergillosis, IgE myeloma, and Sezary syndrome. 
Pulse Oximetry and ABG analysis
Arterial blood gas test : A blood gas test measures the amount of oxygen and carbon dioxide in the blood. It may also be used to determine the pH of the blood, or how acidic it is. The test is commonly known as a blood gas analysis or arterial blood gas (ABG) test. Your red blood cells transport oxygen and carbon dioxide
* Skin testing - To find out type of allergy
Establishing a phenotype in an individual patient. Th1 and Th2 asthma phenotype.
While asthma is a well-recognized condition, there is not one universals agreed upon definition. It is defined by the Global Initiative for Asthma as "a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. The chronic inflammation is associated with airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing particularly at night or in the early morning. These episodes are usually associated with widespread but variable airflow obstruction within the lung that is often reversible either spontaneously or with treatment".

There is currently no precise test for the diagnosis, which is typically based on the pattern of symptoms and response to therapy over time. Asthma may be suspected if there is a history of recurrent wheezing, coughing or difficulty breathing and these symptoms occur or worsen due to exercise, viral infections, allergens or air pollution. Spirometry is then used to confirm the diagnosis. In children under the age of six the diagnosis is more difficult as they are too young for spirometry.
Spirometry

Spirometer- A breathing device

Based on symptoms, response to therapy, spirometry.

Spirometry A lung function test. (to measure breathing capacity and how well you breathe. You will breathe into a device called a spirometer.)  It is recommended to aid in diagnosis and management. It is the single best test for asthma. If the FEV1 measured by this technique improves more than 12% and increases by at least 200 milliliters following administration of a bronchodilator such as salbutamol, this is supportive of the diagnosis. It however may be normal in those with a history of mild asthma, not currently acting up. As caffeine is a bronchodilator in people with asthma, the use of caffeine before a lung function test may interfere with the results. A single -breath diffusing capacity can help differentiate asthma from COPD. It is reasonable to perform spirometry every one or two years to follow how well a person's asthma is controlled.

SPO2


  • Peak Expiratory Flow (PEF)
    • Asthma is often clinically classified according to the frequency of symptoms, forced expiratory volume  in 1 second (FEV1), and peak expiratory flow rate.



  •  Using a device called a peak flow meter, you forcefully exhale into the tube to measure the force of air you can expend out of your lungs. Peak flow monitoring can allow you to monitor how well your asthma is doing at home. 

  • Other supportive evidence includes: a ≥20% difference in peak expiratory flow rate on at least three days in a week for at least two weeks, a ≥20% improvement of peak flow following treatment with either salbutamol, inhaled corticosteroids or prednisone, or a ≥20% decrease in peak flow following exposure to a trigger. Testing peak expiratory flow is more variable than spirometry, however, and thus not recommended for routine diagnosis. It may be useful for daily self-monitoring in those with moderate to severe disease and for checking the effectiveness of new medications. It may also be helpful in guiding treatment in those with acute exacerbations.

    Classification

    • Asthma is classified according to the frequency of symptoms, forced expiratory volume  in one second (FEV1), and peak expiratory flow rate. (PEFR)
    • It may also be classified as atopic or non-atopic, where atopy refers to a predisposition toward developing a type-1 hypersensitivity reaction reaction.
    Clinical classification (≥ 12 years old)
    SeveritySymptom frequencyNight-time symptoms%FEV1 of predictedFEV1 variabilitySABA use
    Intermittent≤2/week≤2/month≥80%<20%≤2 days/week
    Mild persistent>2/week3–4/month≥80%20–30%>2 days/week
    Moderate persistentDaily>1/week60–80%>30%daily
    Severe persistentContinuouslyFrequent (7/week)<60%>30%≥twice/day

    Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic), based on whether symptoms are precipitated by allergens (atopic) or not (non-atopic). While asthma is classified based on severity, at the moment there is no clear method for classifying different subgroups of asthma beyond this system. Finding ways to identify subgroups that respond well to different types of treatments is a current critical goal of asthma research.

    Although asthma is a chronic obstructive condition, it is not considered as a part of chronic obstructive pulmonary disease, as this term refers specifically to combinations of disease that are irreversible such as bronchiectasis and emphysema. Unlike these diseases, the airway obstruction in asthma is usually reversible; however, if left untreated, the chronic inflammation from asthma can lead the lungs to become irreversibly obstructed due to airway remodeling. In contrast to emphysema, asthma affects the bronchi, not the alveoli. The combination of asthma with a component of irreversible airway obstruction has been termed the asthma-chronic obstructive disease (COPD) overlap syndrome (ACOS). Compared to other people with "pure" asthma or COPD, people with ACOS exhibit increased morbidity, mortality and possibly more comorbidities.


    Asthma Exacerbation
    Severity of an acute exacerbation
    Near-fatalHigh PaCo2, or requiring mechanical ventilation, or both
    Life-threatening
    (any one of)
    Clinical signsMeasurements
    Altered level of conciousnessPeak flow  < 33%
    ExhaustionOxygen saturation < 92%
    Arrhythmia PaO2 < 8 kPa
    Low blood pressure "Normal" PaCO2
    Cyanosis 
    Silent chest
    Poor respiratory effort
    Acute severe
    (any one of)
    Peak flow 33–50%
    Respiratory rate ≥ 25 breaths per minute
    Heart rate ≥ 110 beats per minute
    Unable to complete sentences in one breath
    ModerateWorsening symptoms
    Peak flow 50–80% best or predicted
    No features of acute severe asthma


    An acute asthma exacerbation is commonly referred to as an asthma attack. The classic symptoms are shortness of breath, wheezing, and chest tightness,The wheezing is most often when breathing out. While these are the primary symptoms of asthma, some people present primarily with coughing, and in severe cases, air motion may be significantly impaired such that no wheezing is heard. In children, chest pain is often present.

    Signs occurring during an asthma attack include the use of accessory muscles of respiration (sternocleidomastoid  and scalene muscles of the neck), there may be a paradoxical pulse (a pulse that is weaker during inhalation and stronger during exhalation), and over-inflation of the chest. A blue color  of the skin and nails may occur from lack of oxygen.

    In a mild exacerbation the peak expiratory flow rate (PEFR) is ≥200 L/min, or ≥50% of the predicted best. Moderate is defined as between 80 and 200 L/min, or 25% and 50% of the predicted best, while severe is defined as ≤ 80 L/min, or ≤25% of the predicted best.

    Acute severe asthma, previously known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators and corticosteroids. Half of cases are due to infections with others caused by allergen, air pollution, or insufficient or inappropriate medication use.

    Brittle asthma  is a kind of asthma distinguishable by recurrent, severe attacks. Type 1 brittle asthma is a disease with wide peak flow variability, despite intense medication. Type 2 brittle asthma is background well-controlled asthma with sudden severe exacerbations.

    Exercise-induced

    Exercise can trigger bronchoconstriction  both in people with or without asthma. It occurs in most people with asthma and up to 20% of people without asthma. Exercise-induced bronchoconstriction is common in professional athletes. The highest rates are among cyclists (up to 45%), swimmers, and cross-country skiers. While it may occur with any weather conditions, it is more common when it is dry and cold. Inhaled beta2-agonists do not appear to improve athletic performance among those without asthma, however, oral doses may improve endurance and strength.

    Occupational

    Asthma as a result of (or worsened by) workplace exposures is a commonly reported occupational disease. Many cases, however, are not reported or recognized as such. It is estimated that 5–25% of asthma cases in adults are work-related. A few hundred different agents have been implicated, with the most common being: isocyanates, grain and wood dust, colophony, soldering flux, latex, animals, and aldehydes. The employment associated with the highest risk of problems include: those who spray paint, bakers and those who process food, nurses, chemical workers, those who work with animals, welders, hairdressers and timber workers.

    Aspirin-exacerbated respiratory disease

    Aspirin- exacerbated respiratory disease (AERD), also known as aspirin-induced asthma, affects up to 9% of asthmatics. AERD consists of asthma, nasal polyps, sinus disease, and respiratory reactions to aspirin and other NSAID medications (such as ibuprofen and naproxen). People often also develop loss of smell and most experience respiratory reactions to alcohol.

    Alcohol-induced asthma

    Alcohol may worsen asthmatic symptoms in up to a third of people.This may be even more common in some ethnic groups such as the Japanese  and those with aspirin-exacerbated respiratory disease. Other studies have found improvement in asthmatic symptoms from alcohol.

    Non-atopic asthma

    Non-atopic asthma, also known as intrinsic or non-allergic, makes up between 10 and 33% of cases. There is negative skin test to common inhalant allergens. Often it starts later in life, and women are more commonly affected than men. Usual treatments may not work as well. The concept that "non-atopic" is synonymous with "non-allergic" is called into question by epidemiological data that the prevalence of asthma is closely related to the serum IgE level standardized for age and sex (P<0.0001), indicating that asthma is almost always associated with some sort of IgE-related reaction and therefore has an allergic basis, although not all the allergic stimuli that cause asthma appear to have been included in the battery of aeroallergens studied (the "missing antigen(s)" hypothesis). For example, an updated systematic review and meta-analysis of population-attributable risk (PAR) of Chlamydia pneumoniae biomarkers in chronic asthma found that the PAR for C. pneumoniae-specific IgE was 47%.

    Infectious asthma

    When queried, asthma patients may report that their first asthma symptoms began after an acute lower respiratory tract illness. This type of history has been labelled the "infectious asthma" (IA) syndrome,  or as "asthma associated with infection" (AAWI) to distinguish infection-associated asthma initiation from the well known association of respiratory infections with asthma exacerbations. Reported prevalences of IA for adults range from around 40% in a primary care practice  to 70% in a specialty practice treating mainly severe asthma patients. The true population prevalence of IA in adult-onset asthma is unknown because clinicians are not trained to elicit this type of history routinely, and recollection in child-onset asthma is challenging.


    Usual Onset
    • Childhood
    Speciality
    • Pulmonology
    Risk Factor
    • Air pollution and allergens
    Duration
    • Long term
    Differential Diagnosis

    Many other conditions can cause symptoms similar to those of asthma. In children, symptoms may be due to other upper airway diseases such as allergic rhinitis and sinusitis, as well as other causes of airway obstruction including foreign body aspiration, tracheal stenosis, laryngotracheomalacia, vascular rings, enlarged lymph nodes or neck masses. Bronchiolitis and other viral infections may also produce wheezing. According to European Respiratory society, it may not be suitable to label wheezing preschool children with the term "asthma" because there is lack of clinical data on inflammation in airways. In adults, COPD, congestive heart failure, airway masses, as well as drug-induced coughing due to ACE inhibitors may cause similar symptoms. In both populations vocal cord disfunction may present similarly.

    Chronic obstructive airway disease can coexist with asthma and can occur as a complication of chronic asthma. After the age of 65, most people with obstructive airway disease will have asthma and COPD. In this setting, COPD can be differentiated by increased airway neutrophils, abnormally increased wall thickness, and increased smooth muscle in the bronchi. However, this level of investigation is not performed due to COPD and asthma sharing similar principles of management: corticosteroids, long-acting beta-agonists, and smoking cessation. It closely resembles asthma in symptoms, is correlated with more exposure to cigarette smoke, an older age, less symptom reversibility after bronchodilator administration, and decreased likelihood of family history of atopy.


    Lifestyle 
    • Take light food at night.
    • Keep room well ventilated
    • Drink boiled water
    • Mite-proof bedding may help stop  Asthma attack
    • Change the bed sheet frequently and reverse the bed sheet before sleeping at night.
    • Taking bath in hot water with a few drops of Eucalyptus oil added to it. After a bath, external application of few drops of oil over forehead, nose and chest.
    • Should not expose to cold wind or cold water
    • Avoid taking head bath for few days
    • Early to bed and early to rise keeps a man healthy wealthy and wise.
    • Get out of bed, do not cough in sleeping position
    • No stuff toys in room.
    • Take an extra puff of aerosol inhaler
    • Sip hot tea or beverage or sip a glass of warm water
    • Coffee is good, it act as a bronchodilators
    • Use natural preservatives such as salt, sugar and honey.
    • Sleep in prone position : back facing the ceiling and stomach facing the floor.
    • The Routine
      • On waking up, a glass of warm water with half a teaspoon of honey.
      • A half hour's walk
      • Ayurvedic body massage with herbal oils
      • A warm water bath followed by a steam inhalation using peppermint essential oil
      • Two bowls of warm spinach and corn soup with ginger and black pepper for lunch.
      • Black pepper and long pepper decoction with a teaspoon of pure honey after lunch
      • Light yoga exercises in the evening, followed by a foot massage and a dip of your feet in warm water
      • Steam inhalation and a chest massage with sesame oil and a pinch of rock salt.
      • Two bowl of lentil soup for dinner.
      • One teaspoon Triphala with warm water at bedtime.
      Asthmatics must Avoid
      • Dairy products : milk, curd, paneer, butter milk
      • Rice, banana and Maida based foods (noodles, pasta, naan, bread, biscuit, rusk)
      • Cold water or drinks.
      • All kinds of melon, especially water melons.
      • All kinds of fried foods.
      • Heavy dinners
      • All dry fruits, except almonds.
      • Al sour foods including chili chutneys, achars, tomato ketchups etc.
      • Alcohol.
      • Spicy food
      Avoid these food combinations
      • Fruit with curd and dairy product
      • Hot and cold food together such as ice cream with gulab jamun and cold coffee with hot wafers.

    Yoga
    Uttanasana (standing forward bend pose)

           
    Benefits:
    • It is the good yoga pose treating the symptoms of Asthma
    Shavasana or Corpse pose




           Benefits:
    • It helps to control the symptoms of  Asthma
      
    Simhasana / Lion's Breath - सिंहासन



    • Lion's breath releases the tension in your face and helps you blow off some steam. You can do it anytime during a yoga practice.

    Process :
    • Simhasana -Lion Pose- sitting pose, Vajrasana but body be 45 degrees,  keep leg separated lean forward place palm on floor, look upwards, open mouth and forcefully exhale.
    • Start on your knees than sit back into your heels.
    • Spread your fingers out and press your palm into your knees.
    • Take a deep breath in through your nose.
    • Open your mouth, stretch out your tongue, open your eyes wide, and let your breath out through your mouth.
    • Repeat a few times.
    Benefits :
    • Stretches hips, thighs and ankle, calms the mind, relieves stress and fatigue.
    • Relaxes the neck muscles, back pains, and releases stress from the chest, face and mind.
    • It is known as the 'best face exercise' as it increases blood flow to the face and reduces thin lines to the face.
    • Helps to keep away from respiratory infections and halitosis.
    • Keeps the eyes healthy by stimulating the nerves.
    • Stimulates thyroid gland.
    • Extension of spinal-cord releases tension and stress and improves blood supply.


    • Open the mouth and stretch the tongue out towards the chin as far as you can and gaze at the center of the eyebrow for 30 seconds
    • Breathe through the mouth. The strong stimulation during forceful exhalation helps in clearing carbon dioxide so that fresh air can enter the lungs.
    • It is good for throat problems.

                 Fish Pose Matsyasana (मत्स्यासन )



    • The posture is dedicated to Matsya the fish. Incarnation of Vishnu, the source and maintainer of the universe and all things.
    Technique :
    • Sit in a Padmasana
    • Lie flat on the back with the legs on the floor.
    • Exhale, arch the back by lifting the neck and the chest, take the head back and rest the crown on the floor. Drag the head further back by holding the crossed legs with hands and increase the back arch
    • Now take the hands from the legs, bend the arms, hold the elbows, with the hands and rest the forearm on the floor behind the head.
    • Stay in this position for 30 seconds while breathing deeply.
    •  Rest the back of the head  on the floor, lie flat on the back, inhale then come up to Padmasana, release the legs and relax.
    • Recross the legs the other way and repeat the pose for the same way. length of time.

    Benefit : 

    1. The stretched upper body allows unrestricted airflow, thus providing extra oxygen into the lungs.
    2. It expands the bronchial tubes to permit easier breathing. This is especially useful for asthma patients.
    3. The dorsal region is fully extended in this pose and the chest is well expanded. Breathing becomes fuller

    Pranayama (Breathing Exercises)

    CAUTION: Since Pranayama can be very powerful, it is suggested to first learn and practice Pranayama under the guidance of a certified instructor who can see if you are performing them correctly, and make modifications to your technique, as well as answer questions that may come up in the learning process. 

    Sun Piercing Breath - Surya Bhedi Pranayama सूर्यभेदी प्राणायाम



    The Sanskrit word Surya means Sun, which refers to Pingla Nadi. Bheda means to pierce. Surya Bheda means to Pierce or purify Pingla Nadi. Our right nostril is energetically associated with our body's  heating energy, symbolized by the "Sun" and the syllable  HA. Our left nostril with our bodies cooling energy, symbolized by "Moon" and the syllable THA.
    In the average person these energy are typically in conflict, which leads to disquiet and disease. The goal of traditional Hatha Yoga is to integrate and harmonize HA and THA for happiness and health.

    Process :
    • Sit in a comfortable meditative asana.
    • Block your left nostril. and inhale through your right, which is partially open.
    • Perform Moola Bandha and Jalandhar bandha with kumbhaka.
    • Than close the right right and exhale through the left.  nostril.which is partially open.
    • Continue this manner inhale right and exhale left for 1-3 minutes.
    • All the inhalations in Suryabhedi are from the right nostril and all the exhalations from the left nostril.
    • In Suryabhedi the lungs are filled more slowly, steadily, and fuller than in Ujjayi.
    • Repeat the Pranayama 3,5,7,9, times.
    • When the nostril are partially open the respiration is pierced through, that is why this Pranayama is called Surya Bhedi Pranayama.
    • When doing meditate on solar system and see the lustre.
    • In summer Reduce the number of Surya Bhedi Pranayama.
    Asthma


    Benefits :
    • This Pranayama increases body heat.
    • When you inhale solely through the right nostril you generate heat energy, which is sent out, through your body.
    •  It helps your immune system and reduces mucus thus beneficial in Asthma.
    • This is beneficial in curing diseases caused by Vata  and Kapha Doshas
    •  fGoodor worms, leprosy, contagious disease, indigestion and diseases of female.
    • This Pranayama removes dullness and lethargy.
    • This helps in Kundalini awakening, retards the process of aging and reduces weight.
    • For increasing the activity of heart perform this Pranayama without Kumbhaka.. This should be done 20-30 times twice a day to reduce weight.
    • Increases digestive power
    • Soothes and invigorates the nerves
    • Cleans the sinuses.
    • Good for depression
    • Asthma
    • Excessive Sleepiness
    • Hypothyroidism
    • Obesity
    • Syncope
    Precaution :
    • Never practice Surya Bhedi Pranayama after taking food.
    • People suffering from heart disease.
    • Person suffering from low BP will derive benefit but those with high BP or heart trouble, epilepsy should not hold their breath after inhalation (antara kumbha) whilst practicing this pranayama
              In this breathing, technique inhalation is done through the right nostril.

    Bhastrika Pranayama or Bellows breath भस्त्रिका प्राणायाम / Rapid Forceful breathing.


    • Bhastrika means a bellows used in a furnace. Here the air is forcibly drawn in and out as in a blacksmith's bellows. Hence the name. Rapid forceful breathing

    Process :
    • Take a fast vigorous breath and exhale fast and forcefully. One inhalation and one exhalation completes a cycle of  Bhastrika. The sound made resembles air rushing through bellows.
    • Complete at a stretch 10-12 cycles. Then take a slow deep breath.
    • Sacred Vow : While inhaling in the process of doing Bhastrika we have to think that the divine powers are getting filled in us.

    Benefits :
    • Disease like cold, cough, allergy, asthma and respiratory are cured. Health is improved because of the fresh air provided to the body.
    • Improves the lung capacity hence good for asthma.
    • Disease of throat, tonsillitis are cured.
    • Vata, pitta, kapha the three doshas get balanced. So blood is  purified. This helps in the awakening of kundalini power.
    • Bhastrika activates and invigorate the liver, spleen, pancreas and abdominal muscle 
    • Thus digestion is improved,
    • The sinuses are drained, 
    • The eyes feel cool and one has a general sense of exhilaration.
    • Improves low energy levels. 
    • Good for Thyroid Problems
    • Improves lungs health
    • Blood purifier
    • Fat burner
    • Neurological balance.
    • Strengthens immunity
    • Good for cold & Flu
    Contraindications :
    • As a locomotive engine is stoked with coal to generate steam to pull the train, so Bhastrika generates Prana to activate the entire body. 
    • Too much stoking burns out the boiler of the engine, so also too long a practice of Bhastrika wears out the system as the breathing process is forceful.
    • Person with a weak constitution and poor lung capacity should not attempt Bhastrika.
    • Those suffering from ear or eye complaints (pus in the ear, detachment of the retina) should not attempt them either.
    • If the nose starts to bleed or the ears to throb and ache, immediately stop Bhastrika..
    • Bhastrika should not be done by pregnant women.
    • Uncontrolled Hypertension or low BP
    • Cardiovascular disease
    • Major surgery.
    • Glaucoma.
    • Pitta constitution people, (Inner fire element dosha)
    Caution : Those suffering from High BP and heart diseases should not do this pranayama.
                                                           .....................................................
                                "Lord Krishna says in the Bhagavad Gita in body I am Prana Vayu."

    Skull Shining Breath - Kapalbhati Pranayama कपाल भाति 

    Boost your immunity with your breath


    Kapal - Forehead, and ; Bhati - means light, luster
    Kapalbhati is also a -cleansing techniques. It is a milder form of Bhastrika Pranayama. So with this pranayama one becomes luminous and lustrous.. In Kapalbhati inhalation (Pooraka) is to be done with normal force but the expiration (Rechaka) has to be done with as much force as possible. In doing so, all abdominal area gets inward and outward movements.This pranayama can be done for five minutes. In between one can rest for a while.

    Kapal Bhati

    • As it involves breathing in specific ways, some think it is a form of Pranayama. This is advanced breathing exercise should ideally be learned from an experienced teacher., as it is possible to become lightheaded if it is done incorrectly. Once mastered, this breath generates heat and clears the nasal passages.
    • Sacred Vow :Think that we are throwing all diseases out, mental problems of anger, greed, ego, attachments are also getting cleared. Hence we feel peace.
    Process:
    • In this, you inhale passively and exhale actively and forcefully. 
    • Inhalation is slow but the exhalation is vigorous.
    • There is a split second of retention after each exhalation.

       

    Benefits:
    • Face becomes lustrous and attractive. Diseases like asthma, respiratory troubles, allergies, sinus are cured. Disease  of heart brain and lungs get cured.
    • This relieves constipation. obesity, diabetes, acidity, and kidney problems.
    • Organs in abdominal cavity viz intestine, prostrate and kidney, functions more efficiently and develop immunity towards disease.
    • The sinuses are drained, 
    • The eyes feel cool and one has a general sense of exhilaration.
    • The most effective for detoxifying the body and clearing the energy channels.
    • Additionally, it is believed to increase one’s intuition.
    Contraindications :
    • Kapal bhati  generates Prana to activate the entire body. 
    • Those suffering from ear or eye complaints (pus in the ear, detachment of the retina) should not attempt them either.
    • Kapalbhati  should not be done by pregnant women.
    • Uncontrolled Hypertension and low BP.
    • Cardiovascular disease
    • Major surgery
    • Glaucoma.
    • Pitta constitution people.(Inner fire element dosha)
                                         
    Anulom Vilom Pranayama / Alternate Nose Breathing - Nadi Shodhan  / Anolom Vilom अनुलोम विलोम

    Nadi Shodhan Pranayama

    Coming into Balance


    • To practice Nadi Shodhana, sit in a comfortable meditation position. Make a fist with your right hand, then partially re-extend your ring and little fingers. Lightly place the pad of the thumb on your nose just to the right and below the bridge; lightly place the pads of your ring and little fingers on the corresponding flesh on the left side of your nose. Gently pressing with the ring and little fingers to close the left nostril, exhale fully through the right. Then inhale fully through the right, close it with the thumb, release the left nostril, and exhale through it. Inhale through the left nostril, close it with the fingers, release the right nostril, and exhale through it. This completes one round of Nadi Shodhana.


                           

    Nadi is a Sanskrit word meaning “channel” or “flow” and shodhana means “purification.” Therefore, nadi shodhana is primarily aimed at clearing and purifying the subtle channels of the mind-body organism, while balancing its masculine and feminine aspects. 

    Nadi is a tubular organ of the body like an artery or a vein for the passage of Prana or energy. A nadi has three layers like an insulated electric pipe wire. The innermost layer is called sira, the  the middle layer Damani and the entire organ as well as the outer layer is called nadiSodhana meaning purifying or cleansing, so the object of Nadi Sodhana Pranayama is the purification of nerves. A little obstruction in a water pipe  can cut off the supply completely. A little obstruction in the nerve  can cause great discomfort and paralysis of a limb or organ.

    The Nadi Shodhan Pranayama calms and centers the mind by bringing into harmony the left and right hemispheres of the brain which correlate to the logical and emotional sides of our personality. The right nostril represents the Ida nadi and is connected with the left brain. The left nostril represents the Pingala nadi and is connected with the right hemisphere of the brain. When we breathe through the alternate nostril in a specific pattern, it brings the balance between both hemispheres of the brain. Nadi shodhan is clearly a yogi's delight for its instant calming effect.

    Prana breath in through left nostril represents energy of the moon, which symbolizes peace and has a cooling effect. Hence purification of nadis, commences. Begining of this pranayama has to be made by the left nostril.

    Process :
    •  Sit comfortably in an erect position. Keep the head, neck and the spine straight.
    •  Rest the left hand on the left knee.
    •  Close the right nostril with the tip of right thumb.
    • Now breath out slowly through the left nostril.
    • Keeping the right nostril closed breathe in slowly and deeply through the left nostril.
    • Now close the left nostril with ring finger and little finger of the right hand  and slowly breathe out through the right nostril.
    • Now keeping the right nostril still closed, breathe in through the right nostril.
    • This completes one entire round of Anuloma -  Viloma.
    • Repeat the entire process
    • Remember that breathing in and breathing out  should be done very slowly without any noise
    One complete cycle of nadi shodhan Pranayama. Here the rhythm of breathing is as follows:
    • Exhale through the right nostril.
    • b Inhale through the right nostril.
    • c Exhale through the left nostril.
    • d  Inhale through the left nostril.
    • e Exhale through the the right nostril
    • f Inhale through the right nostril.
    • g Exhale through the left nostril.
    • h Inhale through the left nostril
    • i Exhale through the right nostril
    • j Inhale through the right nostril...and so on 
    This should be done for three minutes. If feel tired rest for a while and than resume. Slowly one can extend the time for 10 minutes.. It helps in awakening of Kundalini power. While doing this pranayama one can mentally chant 'om' so the mind becomes calm and gets ready for meditation.
    Benefits
    • Anuloma -Vilom Pranayama cleanses all Nadis which makes the body lustrous and healthy. Diseases occurring due to  the disturbances of Vata Dosha like Rheumatism, gout,  disease pertaining to urinary and reproductive organs are cured.
    • Disease like cold, cataract, sinus are cured.
    • The three doshas assume proper proportion
    • Blockages of the arteries are removed and blood circulation get improved. The practice of this Pranayama regularly for month together removes major blockages preventing the  phenomenon of heart attack.
    • Pathogenic cholesterol, triglycerides, H.D.L and L.D.L  also get controlled making the arterial channels clean for effective and unimpeded flow of blood in the heart.
    • Increases enthusiasm, fearlessness, thus improving positive approach to life.
    • This Pranayama has the effect on cleansing the body and the mind and cures almost all the diseases.
    • Infuses the body with oxygen
    • Clears and releases toxins
    • Reduces stress and anxiety
    • Calms and rejuvenates the nervous system
    • Helps to balance hormones
    • Supports clear and balanced respiratory channels
    • Helps to alleviate respiratory allergies that cause hay fever, sneezing, or wheezing
    • Balances solar and lunar, masculine and feminine energies
    • Fosters mental clarity and an alert mind
    • Enhances the ability to concentrate
    • Brings balance to the left and right hemispheres of the brain
    Effect
    • The blood receives a larger supply of oxygen in Nadi Sodhana than in normal breathing, so that one feels refreshed and the nerves are calmed and purified. The mind becomes still and lucid.
    • Sacred Vow :The result of friction and churning of breath in ida and Pingla Nadis, there is awakening n Sushumna nadi. A  divine light may rise upwards to the Sahasrara Chakra ; A feeling of divine light pervades the whole of the body. We feel that with the Mantra 'Om Brahma' the supreme power is filling us with divine energy. Anuloma-Vilom Pranayama done with this kind  of divine feeling gives better results.

    Caution
    • Persons suffering from high blood pressure or heart trouble should never attempt to hold their breath (kumbhaka).They can practice Nadi Sodhana Pranayama without retention (kumbhaka) with beneficial effect.
    • Person suffering from low blood pressure can do this pranayama with retention after inhalation (antara kumbhaka) only with beneficial effect.

    Ujjayi Pranayama or Hissing Breath / Ocean Breath / Victorious Breath -  उज्जायी  प्राणायाम 

    Pranayama For Cough & Cold

    More than any technique, Ujjayi (also called Victorious Breath) is a clear demonstration of the connection between our breath and emotions. 
    • Ujjayi breath is really interesting because it acts to calm the sympathetic nervous system at the same time as it boosts your oxygen consumption. It is the primary breath used in vinyasa yoga  because it is powerful enough to support a vigorous flow.

    Ujjayi The prefix ud attached to verbs and nouns, means upwards or superiority in rank.It also means blowing or expanding. It conveys the sense of pre-eminence and power. Jaya means conquest, victorytriumph or success.Looked at from  another view point it implies restraint or curbing. Ujjayi is the process in which the lungs are fully expanded and the  chest puffed out like that of a proud conqueror.

    The sacred Vows :
    Sacred vows in Sanskrit is called  'Sankalp' i.e. firm will. A determination to transform a desire into  reality.The mind desires a thing, the intellect shapes it and the will executes it. If all the three are in total unison then the power of the spirit leads its strength and drive. sets transformed into reality.

    Process :
    • Sit in any meditative pose.
    • Contract the muscles of the throat as much as possible. Perform Pooraka and do a sound like snoring.
    • In this, we create a snore like sound in the throat as we inhale and exhale. Many use Ujjayi breathing during their asana practice.
    • In this Pranayama partially close the back of your throat, which covers the windpipe so that as you inhale and exhale through your nose.
    • The air passes through a narrow air passage in your throat, creating the sound  made  by your breath.
    • Inhale air through both nostrils. On doing so the air should touch muscles of the contracted throat.
    •  Through constricted glottis, exhale through left nostril.
    •  In the later stage of practice, one can perform Jalandhar banda and Moola bandha simultaneously and exhale only through left nostril, and exhale only through left nostril..
    Benefit :
    • The chronic problems of  cough, cold and bronchitis are cured. Tonsilitis, thyroid problem, insomnia, tensions,and high blood pressure.
    • This pranayama gives sweet voice with regular practice cures lisping in children. Helps in Kundalini awakening. Any mantra can be chanted in mind.
    • It is quite beneficial in enhancing memory.
    • It infuses body and mind with fresh Prana which is the vital life force.
    • Relief of sinus pressure.
    • Diminish pain due to headache.
    • Strengthening of digestive as well as nervous system.
    • This pranayama aerates the lungs, removes phlegm, gives endurance, soothes the nerves and tones the entire system.
    • Ujjayi without kumbhaka, done in a reclining position, is ideal for persons suffering from high blood pressure or coronary trouble



    •    This technique partially close the back of your throat, which covers the windpipe so that as you inIn hale and exhale through your nose. 
    •     The air passes through a narrow air passage in your throat, creating the sound made by your breathing.
        Benefit:
    •      It is good for the throat.
    Bhramari or Bee humming breath


    Bhramari is derived from the Sanskrit word 'Bhramar' भ्रमर )which means large black bee. While practicing Bhramari Pranayama, a bee like sound is produced and hence the name "Bhramari Pranayama".



    Procedure : In this, you inhale deeply and then make the humming sound as you exhale. It is the action of making a light humming sound while practicing Pranayama, or yogic breathing. The technique of Bhramari pranayama is same as Ujjayi pranayama. The difference is that in Bhramari, during exhalation, a soft humming sound like murmuring of bees  is made.
    • Inhale deeply : 
    • Breath in till the lungs are full of air
    • Close your eyes with fingers
    • Close your ears with the help of thumb
    • Press the forehead with the index fingers lightly
    • Then press the nose bridge with remaining fingers.
    • Concentrate on Ajna Chakra, Close the mouth. Begin slowly, exhale making humming sound like a bee while reciting Om mentally.
    • Exhale slowly with humming sound
    • Feel vibration in head region
    • Repeat 11-21  times
    • Sacred Vow :Think that our individual consciousness is merging with the divine cosmic consciousness and divine blessings is descending on us and wisdom fills our entire being.

    Benefit :
    • With this Pranayama the mind becomes steady, mental tensions, agitation, high blood pressure, heart disease are affected for better.This is also useful in meditation.
    • The humming sound in Bhramari Pranayama is helpful in cases of insomnia.
    • This breathing technique is especially useful for those with hypertension.
    • Calms and quiets the mind
    • It provides relief to a person in case he is feeling hot or have a mild headache.
    • Releases cerebral tension
    • Stimulates the Pineal and pituitary glands, supporting their proper functioning
    • Soothes the nerves
    • Relieves stress and anxiety
    • Dissipates anger
    • Lowers blood pressure
    • Bolsters the health of the throat
    • Strengthens and improves the voice
    • Supports the healing of bodily tissues
    • Induces sound sleep
    • It is quite beneficial for the people suffering from Alzheimer.
                                                        ............................................
      
    Direction: 
    •      Keep your lip gently closed throughout, inhale deeply
    •      Then  hum as you exhale, extending the exhalation as long as possible
    •     Use your abdominal muscles to control the evenness of your breath on exhalation, repeat this three times
    Benefit:
    • It is good for respiratory problems.
    Udgeet Pranayama / Chanting Breathing - Udgeet Pranayama उद्गीत प्राणायाम



    • It is known as "Omkar Japa" means chanting of 'Om'. Udgeet Pranayama is a simple breathing exercise, should be practiced on daily  basis like other recommended Pranayama. Meditate on sacred mantra om. The body and the universal cosmic body are filled with this mantra. Om is the divine energy. It is more beneficial to start asanas and Pranayama practices with om Japa. Breath in and out very slowly with Omkar Japa in mind. The breath is to be slow slow that inhalation and exhalation is to be limited to 1 minute. The breath should be felt deep inside. This state leads to concentration. Gayitri mantra can also be chanted in the same way.This way we can enjoy the state of Samadhi.
    Process :
    • Sit in a comfortable posture and keep your spine, neck and head straight with relaxed shoulders.
    • Place your both hands and knees and keep your fingers in Gyana mudra.
    • Take a deep inhale through your nose, till your diaphragms get filled with air completely.
    • Then slowly exhale the breath from your nose during the exhalation chant the word 'OM'.
    • While chanting the OM sound of O should be longer than M.
    • Repeat it 3-5 times. Slowly you can increase the count.
    If this is practiced at bed time  one will get peaceful sleep without dreams.

    Udgeet Pranayam
                                              
          
    Benefits :
    • It improves memory power and concentration.
    • It controls high blood pressure and the disorder of kidneys.
    • It helps to improve problem related to sleep and bad dreams.
    • Its good for acidity.
    • It relieves tension, anger and anxiety.
    • It calms the mind and brings stability.
    • It improves the digestive system.
    • It reduces falling of hair, premature graying and appearance of wrinkles and diminution of eye sight.               

    • Chanting breathing : Chanting of OUM mantra while breathing. Take a deep breath and simultaneously pronouncing OUM.
      

    Exercise

    • Playing bansuri (a musical instrument), mouth organ or blowing Shankha (Conch) or filling the air in a balloon.
    • Filling air in air pillow with mouth daily before going to bed.
    • Blowing the balloon by mouth
    • Playing mouthorgan instrument.
    Chest exercises
    • At first breath out slowly through slightly parted lips. Breathe in quietly through the nose, taking a short breath while allowing only the lower part of the chest to fill.
    Diaphragmatic high up breathing
    •   Sitting erect on the side of bed, inhale deeply allowing the abdomen to expand against the small pillow or book, press the book or pillow firmly as you exhale. This helps elevate the diaphragm, improves aeration and encourages a cough to dislodge accumulated sputum.
    •     Lie down flat on your back and raise each leg alternately as you exhale. This improves the tone of abdominal muscle.
    •     Lying down on your back, place a book on the abdomen. Puff out the abdomen as far as possible while inhaling. As you exhale pull in the abdomen, bring the book as close as possible to the spinal column. This brings about synchronization of diaphragmatic and abdominal muscle with breathing.

    Carry home message
    When the breath wonders
    The mind is also unsteady
    But when the breath is calmed,
    The mind too will be still, and
    The aspirant achieve long life
    Therefore one should learn
    To control the breath

    Acupressure point


    Shat Karma 
    Cleansing procedure
    • Kapalbhati
    It is an exercise for the purification of nasal passages, bronchial tubes and lungs. It is normal inspiration followed by forceful expiration.
    • Kunjal Kriya (water purification) / Therapeutic vomiting
    Drink 4 glasses of saline water, press the stomach with the left hand. Put the fingers of the right hand to the back of the throat and vomit the water back.
    • Jal Neti (Nasal Cleansing)
    Add tsp of sea salt to a glass of lukewarm water and stir well. With the use of (neti) pot, pour the water into one nostril, keeping the head back. Then raise the head and blow the excess water out of the nostril, repeat on another side. To be practiced daily. 
    Hand Mudra / Seal
    Linga Mudra


    It works by concentrating on the fire element inside the body.
    Formation :
    • Linga mudra is formed by interlocking the palm but keeping the left thumb erect pointing upwards. This mudra can be done by reversing the hand too,
    Effect :
    • The fire in the thumb is activated  and is able to increase uninhibited.
    Benefits : 
    • Asthma, bronchitis, T.B Pleurisy are cured.
    • Hypothermia : Shivering and chills due to cold weather can be controlled. 
    • Discomfort experienced in air conditioned room is relieved by this mudra.
    • Ailments caused by over production of mucus such as wet asthma cold sinusitis etc can be cured.
    • Increased digestive powers and also melts excess of fat in the body. Give better results  when performed together with  Soorya Mudra- both 15 minutes each, one after the other.
    • Difficulty in breathing can be relieved by this mudra.
    • Congested nose can be relieved by this mudra immediately and one can get good sleep.
    • Regulates the flow of menstrual cycle. Give better results when performed  together with surya mudra.- both 15 minutes each , one after other.
    • When naval center is shifted from the original place, comes back to its place by this mudra.
    Special Note : This mudra increases heat in the body so this mudra is to be performed  only for 15 minutes or less. But when there is congestion and cold continues do this mudra for 30 minutes twice a day followed by Prana mudra for 10 minutes.. Since this mudra generates heat  one must consume a lot of  liquids such as water, fruit juices, milk, butter milk etc.
    Any one suffering from acidity, fever and stomach ulcers  should not perform this mudra.
    This mudra is to be performed only  till the problem persists and then it should be discontinued.

    Surya Mudra
    Formation- The tip of the ring finger is to be placed at the base of the thumb and the thumb is to be placed gently on the back of the ring finger. 
    Effect- it generates heat in the body. Good for a cough and Asthma.
    Ganesh Mudra
    • Formation- Hold the left-hand palm facing outwards in front of the chest and bend fingers. Hook the right-hand fingers in the left-hand fingers. Exhale and pull both the hands in opposite directions without releasing the grip. Then inhale let go the tension. Repeat. Then place both the hands on the sternum. Now change the hand position with the right palm facing outward, repeat the steps. 
    • Effect-This Mudra activates the lungs.
    Bandha or Chin lock

    Jalandhar Bandha
    The contraction of the throat and pressing the chin against the breast-bone to form a firm chin-lock is known as Jalandhar Bandha.
    Sit in any comfortable meditative Asana Padmasana, Sukhasana or Vajrasana. The head is bent forward so that chin is pressing the neck. Concentrate on Vishudha  Chakra. This is performed with external breath retention, it should be held as long as the practitioner is able to retain the breath.

    Marma
    Ani and Urvi marma of the upper limb.
    Location- They are located 4 fingers and 8 fingers above elbow joint respectively in both arms. Stimulation- They can be simulated with the help of thumb of opposite hand simultaneously. 
    Effect- It increases the efficiency of thoracic organs i.e. heart, lungs and esophagus.
    Marmas of head and neck religion can also be stimulated.
    Chakra
    Anahata  Chakra
    location- It is located in the region of the heart. Concentration on this chakra will energize lung, heart and Thymus.
    Meditation
    Meditation will help in reducing the stress 
    Avoidance of triggers is a key component of improving control and preventing attacks. The most common triggers include allergens, smoke (from tobacco or other sources), air pollution, non-selective beta blockers, and sulfite-containing foods. (Dry potatoes, gravies, sauces, fruit toppings, maraschino cherries, pickled onions, Maple syrup, jams, jellies, biscuits, bread, pies, pizza dough. Dried apricots, and sometimes grapes will be transported with sachets of the sulfite containing preservative Cigarette smoking and second hand smoke (passive smoke) may reduce the effectiveness of medications such as corticosteroids. Laws that limit smoking decrease the number of people hospitalized for asthma. Dust mite control measures, including air filtration, chemicals to kill mites, vacuuming, mattress covers and others methods had no effect on asthma symptoms. There is insufficient evidence to suggest that dehumidifiers are helpful for controlling asthma.
    Overall, exercise is beneficial in people with stable asthma. Yoga could provide small improvements in quality of life and symptoms in people with asthma. More research is necessary to determine how effective weight loss is on improving quality of life, the usage of health care services, and adverse effects for people of all ages with asthma.
    XXX
    Prevention
    • Follow a disciplined life
    • Get away from trigger
    • Start your medications without waiting for the conditions to aggravate
    • Always  prefer  your own bedspread
    • Half an hour walk daily will reduce the effect of triggers.
    • Immunomodulation the drug like pippali (piper longum), Haridra (Turmeric), Tulsi (Holy Basil), Neem, Guduchi (Tinospora cardifolia) have proved to correct deranged immune system when administered in a specific way.
    • Manage the conditions i.e. if the room is locked for a long  time, then open all the doors and windows of the rooms, keep the bedspread in the sun and room should be cleaned.
    • Do not feel shy to explain your condition, while visiting friends or relatives. The guest always provided with fresh linen from the storage box. This is definite asthma causing a trigger.
    • For food, you should be very specific and say “I take only this”. Mind you, your health is your personal asset and it should remain under your control.
    • If alcohol acts as a trigger say no to it.
    • Wall cleaning should be done routinely like monthly mopping
    • No wall hanging and carpets, Bamboo  mat is preferred.
    • Install electronic chimney in the kitchen.
    • Can have air filter inside room.
    • Avoid air-conditioned theaters 
    • If obese than weight reduction.
    • Decreasing risk factors such as tobacco smoke, air pollution, chemical irritants including perfume, and the number of lower respiratory infections. 
    • Other efforts that show promise include: limiting smoke exposure.
    • Early pet exposure may be useful. Results from exposure to pets at other times are inconclusive and it is only recommended that pets be removed from the home if a person has allergic symptoms to said pet.
    • It is not clear if annual influenza vaccinations affects the risk of exacerbations. Immunization, however, is recommended by the World Health Organization. Smoking bans are effective in decreasing exacerbations of asthma.
    • Symptoms can be prevented by avoiding triggers, such as allergens  and respiratory irritants.
    • Take Asthma Medications as Prescribed.

    While there's no cure, there are steps you can take to keep your asthma in control and prevent an attack.
    1. Identify Asthma Triggers. ...
    2. Stay Away From Allergens. ...
    3. Avoid Smoke of Any Type. ...
    4. Prevent Colds. ...
    5. Allergy-Proof Your Home. ...
    6. Get Your Vaccinations. ...
    7. Consider Immunotherapy Allergy Shots. ...

    Asthma may not be considered fatal, till it is  acute. One has to maintain the  quality of life.

    Management

    While there is no cure for asthma, symptoms can typically be improved. The most effective treatment for asthma is identifying triggers, such as cigarette smoke, pets or other allergens, and eliminating exposure to them. If trigger avoidance is insufficient, the use of medication is recommended. Pharmaceutical drugs are selected based on, among other things, the severity of illness and the frequency of symptoms. Specific medications for asthma are broadly classified into fast-acting and long-acting categories. The medications listed below have demonstrated efficacy in improving asthma symptoms, however "real world" use-effectiveness is limited as around half of people with asthma worldwide remain sub-optimally controlled, even when treated. People with asthma may remain sub-optimally controlled either because optimum doses of asthma medications do not work (called "refractory" asthma) or because individuals are either unable (e.g. inability to afford treatment, poor inhaler technique) or unwilling (e.g., wish to avoid side effects of corticosteroids) to take optimum doses of prescribed asthma medications (called "difficult to treat" asthma). In practice, it is not possible to distinguish "refractory" from "difficult to treat" categories for patients who have never taken optimum doses of asthma medications. A related issue is that the asthma efficacy trials upon which the pharmacological treatment guidelines are based have systematically excluded the majority of people with asthma. For example, asthma efficacy treatment trials always exclude otherwise eligible people who smoke, and smoking blunts the efficacy of inhaled corticosteroids, the mainstay of asthma control management.

    Bronchodilators are recommended for short-term relief of symptoms. In those with occasional attacks, no other medication is needed. If mild persistent disease is present (more than two attacks a week), low-dose inhaled corticosteroids or alternatively, a leukotriene antagonist or a mast cell stabilizer by mouth is recommended. For those who have daily attacks, a higher dose of inhaled corticosteroids is used. In a moderate or severe exacerbation, corticosteroids by mouth are added to these treatments.

    People with asthma have higher rates of anxiety, psychological stress, and depression. This is associated with poorer asthma control. Cognitive behavioral therapy  may improve quality of life, asthma control, and anxiety levels in people with asthma.

    Improving people's knowledge about asthma and using a written action plan has been identified as an important component of managing asthma. Providing educational sessions that include information specific to a person's culture is likely effective. More research is necessary to determine if increasing preparedness and knowledge of asthma among school staff and families using home-based and school interventions results in long term improvements in safety for children with asthma. School-based asthma self-management interventions, which attempt to improve knowledge of asthma, its triggers and the importance of regular practitioner review, may reduce hospital admissions and emergency department visits. These interventions may also reduce the number of days children experience asthma symptoms and may lead to small improvements in asthma-related quality of life. More research is necessary to determine if shared decision making is helpful for managing adults with asthma or if a personalized asthma action plan is effective and necessary. Some people with asthma use pulse oximeters to monitor their own blood oxygen levels during an asthma attack. However, there is no evidence regarding the use in these instances.



    Treatment

    Avoiding triggers. inhaled corticosteroids, salbutamol.

    Bronchial Asthma

    Acute Attack
    Advice
    1. Get out of bed. Do not lie on bed and cough.
    2. Take an extra puff of aerosol inhaler.
    3. Sip some hot tea/ Coffee  or beverage or sip a glass of warm water.
    4. Initiate a short term (5 day) course of Prednisolone 5 mg tablet 2 tab three times a day. If Bronchodilator aerosol is in effective, prolong repeated attacks at night, morning tightness lasts beyond midday, Asthma causes immobilisation even briefly., there is often day to day worsening of the condition. Reduce dose of Prednisolone gradually.
    5. Send for the doctor if attack is severe.
    Treatment at home
    1. Aerosol Inhaler. Technique : 
    • The aerosol inhaler should be placed between the lips. A slow inhalation of total lung capacity  is then taken, the canister been depressed once during early part of the inhalation.
    • The more the patient empties his lung before inhalation, the bigger the dose reaching the lungs and greater the bronchodilation. Unfortunately, breathing out hard  causes many asthmatics to start coughing and can induce bronchospasm and a comprimized should be reached between efficiency and comfort.
    • Holding the breath after inhalation increases the delivery of the drug to the bronchi.
    An interval of one minute is recommended between puffs.
    Severe Acute Asthma
    Diagnostic feature
    1. Lack of response to normal medication.
    2. Inability to talk  or complete a sentence.
    3. Increasing tachycardia and respiratory rate.
    4. Pulses paradoxes
    5. Hypotension
    6.  Silent chest (breath sounds faint and wheeze hardly audible),
    7. Increase  distress and audible.
    8. Respiratory  muscle fatigue (periodical apnea and respiratory alternans)
    9. Cyanosis (If PaO2 falls below 50 mm below Hg)
    Management
    1. Hospitalize
    2. Full assessment  including PEFR or FEV, and arterial blood gas estimation. Chest X-Ray to rule out pneumothorax.
    3. Oxygen at high flow rate (6-8 lit /min)  through nasal prongs or O2 Mask with regular monitoring to prevent hypercapnia
    4. Inj Hydrocortisone 5mg/kg IV 6 hourly    Dose may be doubles if no significant improvement in 8 hours.
    5. Tab Prednisolone 40-60 mg PO
    6. If β2 agonist have not been given  relief through metered dose inhaler, use of nebulizer.   
    Salbutamol or Terbutaline 2.5 mgq 2-4 hour.
    If satisfactory improvement, reduced nebulized salbutamol or terbutaline to 6 hourly.
    Inj Terbutaline0.25-0.5 microg SC or IV over 10 minutes followed by maintenance dose of 12.5 micro g/min
    Note :Cardiac arrythmias can occur if these drugs are  overused.
    If concurrent Bronchitis:
    Nebulize Ipratropium bromide : Add inhalation aerosol 18 micro g per puff.

    Or Budesonide 100mg per metered dose.

    Or  Inj Amino phylline 6mg/kg IV over 30 minutes followed by 0.6-1 mg/kg/h maintaining theophylline blood levels between10-20 mg/L.
    Note : Precaution should be taken in  patients who have  received theophylline in the recurrent past. Major side effects of Theophylline are arrhythmias, fits, severe nausea and vomiting, hypotension and hypokalemia (the last especially with the simultaneous use of  beta2-agonist and corticosteroids.

    Antibiotics
    • If infection (fever, purulent sputum) or ineffective Cough and retention of secretions.

    Note : Avoid sedatives and aspirin, and aspirine related drugs.
    With recovery:
    Nebulizer therapy should be gradually tapered and replaced with  metered dose inhaler or Accuhaler. Oral prednisolone should replace IV Hydrocortisone and patient should be stabilized on drugs he will be taking at home after discharge from hospital.

    If patient does not respond :
    Ventilatory support. Clinical feature of ventilatory failure are -obturate mental state, gasping respirations, silent chest, cyanosis, tachycardia, hypotension, spell of apnea and severe fatigue and exhaustion. PaCo2 is high. Effective intubation and ventilation can be lifesaving.

    In difficult cases with very high airway resistance, it may be impossible to ventilate the patient with a ventilator and the procedure can be carried out using an anesthetic bag. The PaO2 always should be maintained above 50-60 mm hg.

    Ventilatory support should be continued until the parantral and inhaled medications produce significant relief in airways obstruction.
    After attack subsides :
    Tab Salbutamol 4 mg
    or Tab Terbutaline 2.5-5 mg.
    Or Tab Salbutamol-Theophylline 1-1-1
    Grilinctus - one teaspoon at bed time.

    Advice :
    Cessation of smoking Patients and his close relatives must be strongly discouraged from smoking.
    Dust and allergen avoidance.

    Chronic Asthma (In adults)
    Basic principles
    • Avoidance of provoking factors when possible.
    • Selection of best inhaler device.
    • Treatment stepped up as neccessary to achieve control.
    • Treatment stepped down if control of asthma is good.
    • A rescue course of prednisolone may be needed at any time and at any step.
    1
    Occasional use of relief bronchodilators inhaled (salbutamol) as required. If required more than once daily
    Proceed to step 2
    Regular inhaled anti-inflammatory drugs
    Inhaled Salbutamol or Terbutaline.
    Beclomethasone or  Budesonide 100-400 micro g BD
    Formeterol +Beclomethasone.
    If control not achieves, start inhaled corticosteroids.
    Step 3
    • Asthalin (as required)
    • Beclate or Budecort inhaled 800-2000 micro g/day or Fluticasone 400-1000 micro g/day through volume spacer
    • Fluticasone plus salmeterol (Seroflo or Seretide accuhaler) BD.

    Step 4
    High dose inhaled corticosteroids and regular bronchodilator
    • Inhaled Asthalin or Ventolin as required
    • Beclomethasone or Budesonide 800-2000 micro g/day, via volume spacer.
    • Sequential trial of one  or more of the following: 

    Inhaled long acting Beta-agonist
    Acebrophylline 100 mg
    Long acting  beta-agonist tablets
    High dose inhaled bronchodilator
    Cromoglycate or Montelukast 10 mg at bed 

    Step 5
    Addition of Corticosteroids tablets
    • Inhaled Asthalin or Ventolin as required
    • Beclomethasone or Budesonide 800-2000 micro g/day or Fluticasone 400-1000 micro g /day.
    • One or more of long acting bronchodilators
    • Prednisolone tab in single large dose
    Stepping down
    Patient recently started at step 4 or 5
    Reduction may begin after short period of time
    In patient with the chronic Asthma , a 3-6 months period  of stability before slow, stepwise reduction is undertaken. 
    Salmeterol and Fluticasone inhaled 125-250 micro g /day.

    Exercise Induced Asthma
    Regular treatment should include adequate dose of corticosteroids. Double nocturnal dose of Salbutamol and Corticosteroids, and give both through spacing device. If symptoms still occurs, add slow release Theophylline + Montelukast at night.

    Exercise For Asthma And Chronic Bronchitis
    At first breath out slowly through slightly parted lips. Breath in quietly through the nose, taking a short breath while allowing only the lower part of the chest to fill.

    Exercise should be practiced 3 times a day, and a habit of lower chest breathing cultivated at all times.

    Diaphragmatic High Up Breathing :
    1. Sitting erect on the side of the bed, inhale deeply, allowing the abdomen to expand against a small pillow or book. press the book or pillow firmly as you exhale. These help elevate the diaphragm, improves aeration, and encourages cough to dislodge accumulated sputum.
    2. Lie down flat on your back and raise each leg alternately as you exhale. This improves tone of abdominal muscle.
    3. Lying down on your back place a book on your abdomen. Puff out the abdomen, as far as possible while inhaling. As you exhale pull in the abdomen, bring the book as close as possible to the spinal column. This brings about synchronization of diaphragmatic and abdominal muscles with breathing.
    • Avoid exposure to dust/ Pollens / PETS / Pigeons /Smoke
    • Regular Walking/ Exercise/ yoga  
    • Weight reduction/ BMI.
    • Plenty of oral fluids.
    • Salt water Gargling thrice daily (for sore throat)
    • Steam inhalation thrice a day
    • Avoid spicy and cold food
    • Asthma medication include Asthma inhalers and pills and life style changes to treat and prevent asthma attacks.
    • Long acting anti- inflammatory asthma inhalers . These inhalers deliver low doses of steroids to the lungs with minimal side effects if used properly.
    • The fast acting or "rescue" bronchodilators inhaler works immediately on opening airways during an asthma attack.
    • If you have bronchial asthma, make sure your doctor shows you how to use the inhalers properly. Be sure to keep your rescue inhaler with you in case of an asthma emergency.
    • Asthma support group are also available to help you better cope with your asthma.
    • Initiate a short course of steroid  Tab prednisolone.
    • Relaxation of airway smooth muscle..
    • Use of Bronchodilator. Tab salbutamol or Terbutaline
    • Aerosol inhalers (Asthalin, Ventorlin) or Beclomethasone(Beclate). It is advisable to gargle with plain water after use of an inhaler.
    • The inhaler should be placed between the lips. A slow inhalation of total lung capacity is then taken. Holding the breath after inhalation increases the delivery of the drug to the bronchi. An interval of one minute is recommended between puffs.
    • Nebulizer Ipratropium bromide. Add inhalation aerosol 18 mcg per puff.

    • Inj Aminophylline
    • Antibiotics if infection
    • Desensitization is done. Immuno-therapy is given.
    • If the patient does not respond, Ventilator support.
    • Advised cessation of smoking
    Postural Drainage
    For Bronchiectasis
    Instruct the patient to place a chest in the position in which gravity is of  greatest assistance in promoting expectorant. . This varies with each lobe. But since Bronchiectasis usually affects  the lower lobes, the prone position with the head tilted downwards is the most useful.

    A hot drink immediately before postural drainage may help to liquify sputum. Attempt to dislodge the secretion should be made by  coughing and by percussing the affected part of the chest. Drainage should be done for 10 minutes at a time, night and morning.

    Bronchoprovocation provoked by AMP could be effectively inhibited by the mast cell stabilizing agents sodium cromoglycate  and nedocromil sodium 

    In addition, the β2-agonist salbutamol, which is a potent mast cell inhibitor, attenuates AMP-induced bronchoconstriction to a greater extent


    Omalizumab
    Omalizumab is a humanized monoclonal antibody. Omalizumab has demonstrated its efficacy in severe IgE-mediated allergic asthma, 

    Approved indications for omalizumab

    • There is no known cure for asthma, but it can be controlled.
    • Suppressed with the use of inhaled corticosteroids, long acting beta agonists (LABA) or
    • Antileukotriene agents may be used in addition to inhaled corticosteroids if asthma symptoms remain uncontrolled. 
    • Treatment of rapidly worsening symptoms is usually with an inhaled short-acting beta 2 agonist such as salbutamol  and corticosteroids taken by mouth. 
    • In very severe cases, intravenous corticosteroids, magnesium sulphate, and hospitalization may be required.

    In 2019 asthma affected approximately 262 million people and caused approximately 461,000 deaths. Most of the deaths occurred in the developing world . Asthma often begins in childhood, and the rates have increased significantly since the 1960s. Asthma was recognized as early as Ancient Egypt.  The word "asthma" is from the Greek ἆσθμαâsthma, which means "panting".
    Medications
    Salbutamol metered dose inhaler commonly used to treat asthma attacks.

    Medications used to treat asthma are divided into two general classes: quick-relief medications used to treat acute symptoms; and long-term control medications used to prevent further exacerbation. Antibiotics are generally not needed for sudden worsening of symptoms or for treating asthma at any time.

    Medications for asthma exacerbations

    • Short-acting beta2- adrenoceptors  agonist (SABA), such as salbutamol (albuterol ) are the first line treatment for asthma symptoms.They are recommended before exercise in those with exercise induced symptoms.
    • Anticholinergic medications, such as ipratropium, provide additional benefit when used in combination with SABA in those with moderate or severe symptoms and may prevent hospitalizations. Anticholinergic bronchodilators can also be used if a person cannot tolerate a SABA. If a child requires admission to hospital additional ipratropium does not appear to help over a SABA.For children over 2 years old with acute asthma symptoms, inhaled anticholinergic medications taken alone is safe but is not as effective as inhaled SABA or SABA combined with inhaled anticholinergic medication. Adults who receive combined inhaled medications that includes short-acting anticholinergics and SABA may be at risk for increased adverse effects such as experiencing a tremor, agitation, and heart beat palpitations compared to people who are treated with SABA by itself.
    • Older, less selective adrenergic agonists, such as inhaled epinephrine, have similar efficacy to SABAs. They are however not recommended due to concerns regarding excessive cardiac stimulation.
    • Corticosteroids can also help with the acute phase of an exacerbation because of their anti-inflammatory properties. The benefit of systemic and oral corticosteroids is well established. Inhaled or nebulized corticosteroids can also be used. For adults and children who are in the hospital due to acute asthma, systemic (IV) corticosteroids improve symptoms. A short course of corticosteroids after an acute asthma exacerbation may help prevent relapses and reduce hospitalizations.
    • Other remedies, less established, are intravenous or nebulized magnesium sulfate and helium mixed with oxygen. Aminophylline could be used with caution as well.
    • Mechanical ventilation is the last resort in case of severe hypoxemia.
    • Intravenous administration of the drug aminophylline does not provide an improvement in bronchodilation when compared to standard inhaled beta-2 agonist treatment. Aminophylline treatment is associated with more adverse effects compared to inhaled beta-2 agonist treatment.

    Long term control
    Fluticasone propionate metered dose inhaler commonly used for long term control.

    • Corticosteroids are generally considered the most effective treatment available for long-term control. Inhaled forms are usually used except in the case of severe persistent disease, in which oral corticosteroids may be needed. Dosage depends on the severity of symptoms. High dosage and long term use might lead to the appearance of common adverse effects which are growth delay, adrenal suppression, and osteoporosis. Continuous (daily) use of an inhaled corticosteroid, rather than its intermitted use, seems to provide better results in controlling asthma exacerbations. Commonly used corticosteroids are budesonide,fluticasone,mometasone and ciclesonide.

    • Long-acting beta-adrenoceptor agonists (LABA) such as salmeterol and formoterol can improve asthma control, at least in adults, when given in combination with inhaled corticosteroids. In children this benefit is uncertain. When used without steroids they increase the risk of severe side effects, and with corticosteroids they may slightly increase the risk. Evidence suggests that for children who have persistent asthma, a treatment regime that includes LABA added to inhaled corticosteroids may improve lung function but does not reduce the amount of serious exacerbations. Children who require LABA as part of their asthma treatment may need to go to the hospital more frequently.
    • Leukotriene receptor antagonists (anti-leukotriene agents such as montelukast and zafirlukast) may be used in addition to inhaled corticosteroids, typically also in conjunction with a LABA. For adults or adolescents who have persistent asthma that is not controlled very well, the addition of anti-leukotriene agents along with daily inhaled corticosteroids improves lung function and reduces the risk of moderate and severe asthma exacerbations. Anti-leukotriene agents may be effective alone for adolescents and adults, however there is no clear research suggesting which people with asthma would benefit from anti-leukotriene receptor alone. In those under five years of age, anti-leukotriene agents were the preferred add-on therapy after inhaled corticosteroids. A 2013 Cochrane systematic review concluded that anti-leukotriene agents appear to be of little benefit when added to inhaled steroids for treating children. A similar class of drugs, 5-LOX  inhibitors, may be used as an alternative in the chronic treatment of mild to moderate asthma among older children and adults. As of 2013 there is one medication in this family known as zileuton.
    • Mast cell stabilizers  (such as cromolyn sodium ) are safe alternatives to corticosteroids but not preferred because they have to be administered frequently.
    • Oral Theophyllines  are sometimes used for controlling chronic asthma, but their used is minimized because of their side effects.
    • Omalizumab, a monoclonal Antibody Against IgE, is a novel way to lessen exacerbations by lessening the levels of circulating IgE that play a significant role at allergic asthma.
    • Anticholinergic medications such as ipratropium bromide have not been shown to be beneficial for treating chronic asthma in children over 2 years old, but is not suggested for routine treatment of chronic asthma in adults.
    • There is no strong evidence to recommend chloroquine  medication as a replacement for taking corticosteroids by mouth (for those who are not able to tolerate inhaled steroids). Methotrexate is not suggested as a replacement for taking corticosteroids by mouth ("steroid sparing") due to the adverse effects associated with taking methotrexate and the minimal relief provided for asthma symptoms.
    • Macrolide antibiotics, particularly the azalide macrolide azithromycin, are a recently added GINA-recommended treatment option for both eosinophilic and non-eosinophilic severe, refractory asthma based on azithromycin's efficacy in reducing moderate and severe exacerbations combined. Azithromycin's mechanism of action is not established, and could involve pathogen- and/or host-directed anti-inflammatory activities. Limited clinical observations suggest that some patients with new-onset asthma and with "difficult-to-treat" asthma (including those with the asthma-COPD overlap syndrome - ACOS) may respond dramatically to azithromycin. However, these groups of asthma patients have not been studied in randomized treatment trials and patient selection needs to be carefully individualized.

    For children with asthma which is well-controlled on combination therapy of inhaled corticosteroids  (ICS) and long-acting beta2-agonists (LABA), the benefits and harms of stopping LABA and stepping down to ICS-only therapy are uncertain. In adults who have stable asthma while they are taking a combination of LABA and inhaled corticosteroids (ICS), stopping LABA may increase the risk of asthma exacerbations that require treatment with corticosteroids by mouth. Stopping LABA probably makes little or no important difference to asthma control or asthma-related quality of life. Whether or not stopping LABA increases the risk of serious adverse events or exacerbations requiring an emergency department visit or hospitalisation is uncertain.


    Delivery methods

    Medications are typically provided as metered dose inhalers  (MDIs) in combination with an asthma spacer or as a dry powder inhaler. The spacer is a plastic cylinder that mixes the medication with air, making it easier to receive a full dose of the drug. A nebulizer  may also be used. Nebulizers and spacers are equally effective in those with mild to moderate symptoms. However, insufficient evidence is available to determine whether a difference exists in those with severe disease. For delivering short-acting beta-agonists in acute asthma in children, spacers may have advantages compared to nebulisers, but children with life-threatening asthma have not been studied. There is no strong evidence for the use of intravenous LABA for adults or children who have acute asthma. There is insufficient evidence to directly compare the effectiveness of a metered-dose inhaler attached to a homemade spacer compared to commercially available spacer for treating children with asthma.

    Adverse effects

    Long-term use of inhaled corticosteroids at conventional doses carries a minor risk of adverse effects. Risks include thrush, the development of cataracts, and a slightly slowed rate of growth. Rinsing the mouth after the use of inhaled steroids can decrease the risk of thrush. Higher doses of inhaled steroids may result in lower bone mineral density.

    Others

    Inflammation in the lungs can be estimated by the level of exhaled nitric acid. The use of exhaled nitric oxide levels (FeNO) to guide asthma medication dosing may have small benefits for preventing asthma attacks but the potential benefits are not strong enough for this approach to be universally recommended as a method to guide asthma therapy in adults or children.

    When asthma is unresponsive to usual medications, other options are available for both emergency management and prevention of flareups. Additional options include:

    • Humidified Oxygen  alleviate hypoxia if saturations fall below 92%.
    • Corticosteroid by mouth are recommended with five days of prednisone being the same 2 days of dexamethasone. One review recommended a seven-day course of steroids.
    • Magnesium sulphate  intravenous treatment increases bronchodilation when used in addition to other treatment in moderate severe acute asthma attacks. In adults intravenous treatment results in a reduction of hospital admissions. Low levels of evidence suggest that inhaled (nebulised) magnesium sulfate may have a small benefit for treating acute asthma in adults. Overall, high quality evidence do not indicate a large benefit for combining magnesium sulfate with standard inhaled treatments for adults with asthma.
    •  Heliox, a mixture of helium and oxygen, may also be considered in severe unresponsive cases.Intravenous salbutamol is not supported by available evidence and is thus used only in extreme cases.
    • Methylxanthines  (such as theophylline) were once widely used, but do not add significantly to the effects of inhaled beta-agonists. Their use in acute exacerbations is controversial.
    • The dissociative anesthetic ketamine is theoretically useful if intubation and mechanical ventilation is needed in people who are approaching respiratory arrest; however, there is no evidence from clinical trials to support this.
    • For those with severe persistent asthma not controlled by inhaled corticosteroids and LABAs, bronchial thermoplasty  may be an option. It involves the delivery of controlled thermal energy to the airway wall during a series of bronchoscopies. While it may increase exacerbation frequency in the first few months it appears to decrease the subsequent rate. Effects beyond one year are unknown.
    • Monoclonal antibody  injections such as mepolizumab , dupilumab, omalizumab may be useful in those with poorly controlled atopic asthma. However, as of 2019 these medications are expensive and their use is therefore reserved for those with severe symptoms to achieve cost-effectiveness. Monoclonal antibodies targeting interleukin-5  (IL-5) or its receptor (IL-5R), including mepolizumab, reslizumab, benralizumab, in addition to standard care in severe asthma is effective in reducing the rate of asthma exacerbations. There is limited evidence for improved health-related quality of life and lung function.
    • Evidence suggests that sub-lingual immunotherapy in those with both allergic rhinitis and asthma improve outcomes.
    • It is unclear if non-invasive positive pressure ventilation in children is of use as it has not been sufficiently studied.

    Adherence to asthma treatments

    Staying with a treatment approach for preventing asthma exacerbations can be challenging, especially if the person is required to take medicine or treatments daily. Reasons for low adherence  range from a conscious decision to not follow the suggested medical treatment regime for various reasons including avoiding potential side effects, misinformation, or other beliefs about the medication. Problems accessing the treatment and problems administering the treatment effectively can also result in lower adherence. Various approaches have been undertaken to try and improve adherence to treatments to help people prevent serious asthma exacerbations including digital interventions.

    Alternative Medicine

    Many people with asthma, like those with other chronic disorders, use alternative treatments surveys show that roughly 50% use some form of unconventional therapy. There is little data to support the effectiveness of most of these therapies.
    Evidence is insufficient to support the usage of vitamin C or Vitamin E for controlling asthma. There is tentative support for use of vitamin C in exercise induced bronchospasm. Fish oil dietary supplements (marine n-3 fatty acids) and reducing dietary sodium do not appear to help improve asthma control. In people with mild to moderate asthma, treatment with vitamin D supplementation or its hydroxylated metabolites does not reduce acute exacerbations or improve control. There is no strong evidence to suggest that vitamin D supplements improve day-to-day asthma symptoms or a person's lung function. There is no strong evidence to suggest that adults with asthma should avoid foods that contain monosodium glutamate (MSG). There have not been enough high-quality studies performed to determine if children with asthma should avoid eating food that contains MSG.
    Acupuncture is not recommended for the treatment as there is insufficient evidence to support its use. Air ionisers show no evidence that they improve asthma symptoms or benefit lung function; this applied equally to positive and negative ion generators. Manual therapies, including osteopathic, chiropractic, physiotherapeutic and respiratory therapeutic maneuvers, have insufficient evidence to support their use in treating asthma. The Buteyko breathing technique for controlling hyperventilation may result in a reduction in medication use; however, the technique does not have any effect on lung function. Thus an expert panel felt that evidence was insufficient to support its use. There is no clear evidence that breathing exercises are effective for treating children with asthma.

    Tab Pantocid 40 mg once For 1 week (before food)  1 0 0 (reduces the amount of acid production)

    Tab Augmentin Duo 625 mg 1 0 1 for 1 week (Augmentin Clavulanic acid) Antibiotic for Pneumonia

    ASCORIL-D (For Dry cough)

    Tab LEVOFLOX  500mg once for 1 week 1 0 0 (Bacterial infection)

    Tab Mucinac 600 mg 1 0 1 For 1 Week (mix with water) (Excess mucus production) Mucolytic agent.

    Syp Reswas 10 ml 1 0 1 For 1 Week (Dry Cough)

    Tab Pulmoclear 100/600  mg once for 2 weeks 1 0 0 Acebrophylline 100 mg + Acetylcysteine 600 mg Fourrts India. (Treatment of COPD)

    Piriton CS Syrup 100ml (Treatment of dry cough)

    Tab Cepodem 200 mg (Treatment of Bacterial Infections)

    Tab CEPODEM 325 MG Once for five days

    Tab TELEKAST-L Once for 3 month. Montelukast 10 mg+ Levocetrizine Hydrochloride 5 mg

    BUDAMATE 200 MCG TRANSINHALOR 2 PUFF Twice for 1 Month

    1 puff twice for 2 month (Gargle after procedure)

    Tab ACEBROPHYLLINE SR 200 MG For two weeks AB PHYLLINE-SR  mucolytic and bronchodilator. It works by relaxing the muscles of the airways and also thins and loosens mucus, ...

    Tab PREDMET 16 MG Twice for 5 Days.

    Tab Mondeslor once for 2 week 0 0 1 (Sneezing and runny nose due to allergies.)


    Syp Corex DX 10 ML Twice for two week 1 0 1 (Dry Cough)

    Taxim powder for oral suspension 50mg (to treat bacterial infections)

    Emeset syrup (To control vomiting)

    Montair LC Kid Syrup 60 ml (Anti Asthmatic for treatment of Allergy symptoms. Symptom of sneezing , running nose)


    Nasoclear nasal spray 20 ml

    Tab Levoday 250 mg 

    Tab SOMPRAZ 40 MG Once for five days (before food) used in the treatment of Gastroesophageal reflux disease (Acid reflux),Peptic ulcer disease,Zollinger-Ellison syndrome.

    Tab Omeprazole 40 mg (Same as above)


    Ayurveda
    Panchkarma
    Chyawanprash one tsf trice a day.
    1. Mix a cup of fenugreek decoction, a little honey and a spoonful of ginger juice. Consuming this mixture is beneficial in asthma attack treatment.
    2. To reduce the attack of asthma, mix two teaspoons of honey and one spoon turmeric and consume it.
    3. Garlic intake is very useful in asthma treatment. Boil four to five garlic buds in 30 liters of milk and eat it daily. Apart from this, grind two buds of garlic and mix it in ginger tea. Drinking this tea in the morning also benefits.
    4. Drinking hot coffee also provides relief in asthma. The breathing tube gets cleaned by coffee, which does not make breathing difficult.
    5. Put a little bit of camphor in mustard oil and heat it and after cooling it massage the waist and chest. Asthma symptoms start decreasing when massage with this oil every day.
    6. To treat asthma with natural remedies, take few dry leaves of peepal tree and burn them in a vessel. Now after the burn, filter these burnt leaves by a cloth. Now mix honey with this and consume. Asthma patient gets relief when this treatment is done two to three times a day for two months.
    7. Put the basil leaves in the water and grind it, then mix two teaspoons of honey and eat it. This home remedy provides relief in asthma.
    8. Cardamom is also beneficial in the treatment of asthma attack. Eating large cardamom gives comfort from both asthma and hiccup. Take large cardamom, dates and grapefruit in equal amounts and grind them. Mix it with honey and consume. It removes asthma and cough.
    9. Turmeric late : or Haldi dudh : Mix one spoonful of turmeric powder in a glass of milk and consume it. This Ayurvedic remedy keeps bronchial asthma and allergy under control.
    10. Drink ten to twelve glasses of water daily and do not drink water while eating.
    11. Put two spoonful amla powder in one cup, then add one teaspoon of honey to it and mix it well. Consume this mixture daily in the morning.
    12. Put four to five cloves in half glasses of water and boil for five minutes, then filter it and add some honey and drink it. This ayurvedic treatment of asthma can be done twice a day to three times a day.
    13. Mix one third of the spinach juice and two thirds of carrot juice and drink a glass every day. Use of Bathua (Chenopodium Album), garlic, barley and ginger is beneficial for asthmatics.
    Naturopathy
    Fasting is advised in treating the disorders  like Bronchial Asthma..

    Prognosis

    The prognosis for asthma is generally good, especially for children with mild disease. Mortality has decreased over the last few decades due to better recognition and improvement in care. In 2010 the death rate was 170 per million for males and 90 per million for females. Rates vary between countries by 100 fold.Globally it causes moderate or severe disability in 19.4 million people as of 2004 (16 million of which are in low and middle income countries). Of asthma diagnosed during childhood, half of cases will no longer carry the diagnosis after a decade. Airway remodeling is observed, but it is unknown whether these represent harmful or beneficial changes. Early treatment with corticosteroids seems to prevent or ameliorates a decline in lung function. Asthma in children also has negative effects on quality of life of their parents.

    Epidemiology
    In 2019, approximately 262 million people worldwide were affected by asthma and approximately 461,000 people died from the disease. Rates vary between countries with prevalences between 1 and 18%. It is more common in developed  than developing countries. One thus sees lower rates in Asia, Eastern Europe and Africa. Within developed countries it is more common in those who are economically disadvantaged while in contrast in developing countries it is more common in the affluent. The reason for these differences is not well known. Low and middle income countries make up more than 80% of the mortality.
    While asthma is twice as common in boys as girls, severe asthma occurs at equal rates.In contrast adult women have a higher rate of asthma than men  and it is more common in the young than the old. 
    Global rates of asthma have increased significantly between the 1960s and 2008 with it being recognized as a major public health problem since the 1970s. Rates of asthma have plateaued in the developed world since the mid-1990s with recent increases primarily in the developing world. Asthma affects approximately 7% of the population of the United States and 5% of people in the United Kingdom Canada, Australia and New Zealand have rates of about 14–15%.
    The average death rate from 2011 to 2015 from asthma in the UK was about 50% higher than the average for the European Union and had increased by about 5% in that time. Children are more likely see a physician due to asthma symptoms.
    Population-based epidemiological studies describe temporal associations between acute respiratory illnesses, asthma, and development of severe asthma with irreversible airflow limitation (known as the asthma-chronic obstructive pulmonary disease "overlap" syndrome, or ACOS). Additional prospective population-based data indicate that ACOS seems to represent a form of severe asthma, characterised by more frequent hospitalisations, and to be the result of early-onset asthma that has progressed to fixed airflow obstruction.

    History

    Asthma was recognized in ancient Egypt and was treated by drinking an incense  mixture known as kyphi.  It was officially named as a specific respiratory problem by Hippocrates circa 450 BC, with the Greek word for "panting" forming the basis of our modern name.In 200 BC it was believed to be at least partly related to the emotions. In the 12th century the Jewish physician-philosopher Maimonides wrote a treatise on asthma in Arabic, based partly on Arabic sources, in which he discussed the symptoms, proposed various dietary and other means of treatment, and emphasized the importance of climate and clean air. Chinese Traditional Medicine also offered medication for asthma, as indicated by a surviving 14th century manuscript curated by the Wellcome Foundation.  In 1873, one of the first papers in modern medicine on the subject tried to explain the pathophysiology of the disease while one in 1872, concluded that asthma can be cured by rubbing the chest with chloroform liniment. Medical treatment  in 1880 included the use of intravenous doses of a drug called pilocarpine. In 1886, F. H. Bosworth theorized a connection between asthma and hay fever . Epinephrine was first referred to in the treatment of asthma in 1905. Oral corticosteroids began to be used for this condition in the 1950s while inhaled corticosteroids and selective short acting beta agonist came into wide use in the 1960s. A well-documented case in the 19th century was that of young Theodore Roosevelt  (1858–1919). At that time there was no effective treatment. Roosevelt's youth was in large part shaped by his poor health partly related to his asthma. He experienced recurring nighttime asthma attacks that felt as if he was being smothered to death, terrifying the boy and his parents. During the 1930s to 1950s, asthma was known as one of the "holy seven" psychosomatic illnesses. Its cause was considered to be psychological, with treatment often based on psychoanalysis and other talking cures. As these psychoanalysts interpreted the asthmatic wheeze as the suppressed cry of the child for its mother, they considered the treatment of depression to be especially important for individuals with asthma. In January 2021, an appeal court in France  overturned a deportation order against a 40-year-old Bangladeshi man, who was a patient of asthma. His lawyers had argued that the dangerous levels of pollution in Bangladesh could possibly lead to worsening of his health condition, or even premature death.  Medicine as suggested above should only be taken under the consultation and supervision of registered medical practitioner.  https://madhuchhandacdmo.blogspot.com/2023/09/bronchial-asthma-tamaka-swasa-dama.html



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